Determining factors of renal dysfunction during cisplatin chemotherapy

Comment on Cisplatin-Induced Renal Impairment

Investigations of renal function using the level of neutrophil gelatinase-associated lipocalin associated with single-dose of cisplatin during chemotherapy

Background: Neutrophil gelatinase-associated lipocalin (NGAL) is known as a primary indicator of acute and chronic renal and can be effective in chronic kidney injury (CKI) with kidney tumors cisplatin (CP) chemotherapy. The aim of this study was to evaluate serum and urinary biomarker including NGAL (sNGAL and uNGAL) in canine with solid renal tumors who suffered from cisplatin after short and...

[Determining factors in patient satisfaction with erectile dysfunction treatment].

INTRODUCTION Erectile dysfunction (ED) is associated with depression, anxiety and loss of self-esteem, deteriorating patient's quality of life. The present study aimed, to identify and evaluate key factors influencing patient's satisfaction with ED treatment. To analyze which of them have a greater impact on patient's self-esteem and satisfaction with different aspects of life. METHODS The ap...

Factors determining outcome of acute renal failure patients.

OBJECTIVE Acute Renal Failure (ARF) is a common medical problem. Delay in diagnosis is associated with increased mortality. Variety of conditions can lead to ARF. Many factors can influence the outcome of ARF. This study was done to find the predictive factors related to outcome of ARF. METHODS One hundred adult patients of acute renal failure admitted to Ziauddin Hospital were studied. Certa...

Erythropoietin ameliorates renal dysfunction during endotoxaemia.

BACKGROUND Sepsis has a high mortality (50-80%) when associated with acute renal failure (ARF). Oxidant injury and proinflammatory cytokines and chemokines have been shown to increase with endotoxaemia-related ARF. Since erythropoietin (EPO) has been demonstrated to possess anti-oxidant and anti-inflammatory properties, EPO may have therapeutic efficacy for treating ARF associated with endotoxa...